Bryan was the victim of a brutal two-pronged attack from Sami Zayn and Kevin Owens, who followed up their assault on Shane McMahon with one on Bryan, who had only been cleared to return to competitive action hours earlier.
If Bryan is unable to make it, it could mean the show goes on without either of its two authority figures, which could lead to all kinds of mayhem.
Add in the potential return of the suspended "Yep movement" duo and the penultimate SmackDown before WrestleMania could become a powder keg.
Roode & Orton face Mahal & Singh
Bobby Roode and Randy Orton will form an uneasy alliance tonight to take on Jinder Mahal and his long-time associate Sunil Singh.
Singh is rarely involved in matches in his own right and has become accustomed to being the whipping boy for Mahal's various opponents, so if he can be isolated then victory will surely belong to Roode and Orton.
Unless, that is, they cannot put their differences behind them to form a cohesive unit to take out the Mahal-shaped threat to their United States title match.
The New Day seek Bludgeon Brothers vengeance
Xavier Woods and Kofi Kingston are back in action after two weeks out due to injuries sustained at the mallet-wielding hands of the Bludgeon Brothers.
Harper and Rowan have acted as a two-man wrecking crew in the SmackDown tag division but the four-time champions get a chance to take them down a notch in tag action tonight.